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. 2015 Aug 1;26(15):2788–2800. doi: 10.1091/mbc.E15-01-0018

TABLE 1:

Affected proteins and structures in select N-DRC mutant strains.

Strain Affected N-DRC subunitsa Affected N-DRC structural domainsb
pf2 DRC3-7, (8–10), 11 Entire proximal and distal lobe, L1 and L2 protrusions, OID linker, central linker, base plate protrusion
pf3 DRC1, 2, (3, 4), 5, 6, (7–10), 11 Entire proximal and distal lobe, (L1) and L2 protrusions, (OID linker), (central linker), entire base plate
sup-pf-3 DRC(3–9), 11 Entire proximal and distal lobe, (L1) and L2 protrusions, (OID linker), (central linker)
sup-pf-4 DRC5, 6 Part of distal lobe, L2 protrusion
sup-pf-5 DRC1, 2, 5, 6 Not determined
drc3 DRC3 Part of distal lobe, L1 protrusion

Data for strains other than drc3 are from Table 3 of Piperno et al. (1994), Table 3 of Heuser et al. (2009), and Supplemental Table 4 of Bower et al. (2013).

aProteins in parentheses are reduced.

bStructures in parentheses are reduced.