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. 2015 Aug 1;26(15):2858–2872. doi: 10.1091/mbc.E14-09-1352

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© 2015 Di Donato et al. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

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FIGURE 10: — Model based on our experimental findings. Androgen or NGF induces association of TrkA/β1 integrin/AR/FlnA /PI3-K δ complex, which in turn triggers Rac activation and neuritogenesis in cells challenged with androgens or NGF. Images show the cytoskeleton changes induced by 10 nM R1881 in quiescent PC12 cells.