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. 2015 Mar 6;18(8):pyv005. doi: 10.1093/ijnp/pyv005

Figure 5.

Figure 5.

7-Nitroindazole (7-NI) and URB597 (URB) attenuated fear behavior in nitric oxide synthase (iNOS) knockout (KO) mice. A) 7-NI 30mg/kg administered before the first reexposure to the chamber attenuated fear behavior in wild-type (WT) and KO mice. Results are expressed as means±SEM. Student Newman-Keuls (S-N-K) *P<.05 different from other groups; #P<.05 compared with respective control group; n=7=11/group. B) KO mice presented extinction deficits and URB 3mg/kg facilitate this behavior. URB 3mg/kg also facilitated extinction in WT mice. Results are expressed as means±SEM. S-N-K *P<.05 different from other groups; #P<.05 KO mice different from WT mice; n= 7–9/group.