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. 2015 Mar 6;18(8):pyv005. doi: 10.1093/ijnp/pyv005

Figure 7.

Figure 7.

Expression of cannabinoid receptors type 1 (CB1) and 2 (CB2), monoacylglycerol lipase (MAGL), and fatty acid amide hydrolase (FAAH) mRNA in the medial prefrontal cortex (MPFC) (A-D) and hippocampus (HIP) (E-H) of wild-type (WT) and inducible nitric oxide synthase (iNOS) knockout (KO) mice. In the MPFC, KO nonconditioned (NC) presented higher CB1 (A) and CB2 (B) mRNA than WT NC, whereas conditioning decreased both CB1 and CB2 mRNA in KO mice compared with KO NC (n=5–8/group), KO NC presented lower MAGL (C) and FAAH (D) mRNA than WT NC, whereas conditioning increased both MAGL and FAAH mRNA in KO conditioned (C) compared with KO NC (n=6–8/group). Results are expressed as means±SEM. Student’s t test, *P<.05. In the HIP, KO NC presented lower CB1 (E) and CB2 (F) mRNA than WT NC, and conditioning decreased the CB2 mRNA level in WT compared with WT NC (n=6–8/group); conditioning increased MAGL (G) and FAAH (H) mRNA in WT mice compared with WT NC (n=7–8/group). Results are expressed as percentage means±SEM of control values. Student’s t test, *P<.05.