Table 4.
Cox's proportional hazards regression analysis-resected patients (n = 168)
| Variable | Univariable | Multivariable | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| Age (ref: < 65 years) | 0.90 | 0.57–1.43 | 0.51 | |||
| Male Gender (ref: female) | 1.13 | 0.71–1.79 | 0.60 | |||
| CCI >5 (ref: < 5) | 1.13 | 0.51–2.46 | 0.76 | |||
| CA19-9 category | ||||||
| Normal: ≤35 | ref | ref | ref | |||
| Low: 36–200 | 0.88 | 0.49–1.62 | 0.70 | |||
| Moderate: 201–1000 | 1.33 | 0.61–2.14 | 0.69 | |||
| High: >1000 | 1.34 | 0.58–3.08 | 0.50 | |||
| Elevated Preop CA19-9 > 35 (ref: < 35) | 1.67 | 1.05–2.67 | 0.03 | 1.74 | 1.08–2.81 | 0.02 |
| Borderline Resectable (ref: resectable) | 1.42 | 0.89–2.26 | 0.14 | 1.55 | 0.97–2.48 | 0.07 |
| Node positive (ref: node negative) | 1.43 | 0.88–2.34 | 0.14 | 1.37 | 0.84–2.24 | 0.21 |
| Rec'd Adjuvant therapy (ref: no) | 0.82 | 0.51–1.31 | 0.40 | |||
HR, hazard ratio; CI, confidence interval; CCI, Charlson's comorbidity index; CA, carbohydrate antigen.