Fig. 1.

Photomicrographs detailing the extent of the damage to the MD at P4 (A), in adulthood rats which had bilateral lesions performed at P4 (B), and also the extent of the damage to the MD and to the ATN in adult rats (C). Numbers represent distance from bregma. (D) Assessment of early MD lesion at postnatal day 4 (P4) effect on pyramidal cells development in the prefrontal cortex. Abbreviations: CG1 = cingulate area 1 cortex; PL = prelimbic cortex; IL = infralimbic cortex. ** and ##: p < 0.01. The “*” refers to the control vs MD lesion group comparison and the “#” refers to the MD sham vs MD lesion group comparison.