In the FtsQ structure (Protein Data Bank code 2VH1) residues Lys-218, Leu-226, Tyr-248, and Ser-250 are located in the direct vicinity of a patch of arginine, tryptophan, and tyrosine residues, indicated by a dotted circle. Color coding is based on amino acid preference in PPI hot spots as described by Bogan and Thorn (48). Red, Arg, Trp, and Tyr; pink, Ile, Aps, His, Pro, and Lys; light blue, Met, Phe, Gln, Glu, Asn, and Ala; dark blue, Cys, Val, Leu, Ser, Thr, and Gly. Models were created using PyMOL (49).