Table 2.
TTF-1 expression and EGFR gene mutation status in lung adenocarcinomas of 200 patients
| Category | TTF-1
|
EGFR
|
||||
|---|---|---|---|---|---|---|
| Positive (%) | Negative (%) | P-value | Positive (%) | Negative (%) | P-value | |
| Age | ||||||
| >61 years | 75 (79.8) | 19 (20.2) | 0.557 | 40 (42.6) | 54 (57.4) | 0.602 |
| ≤61 years | 88 (83.0) | 18 (17.0) | 49 (46.2) | 57 (53.8) | ||
| Sex | ||||||
| Male | 54 (71.1) | 22 (28.9) | 0.004 | 23 (30.3) | 53 (69.7) | 0.000 |
| Female | 109 (88.0) | 15 (22.0) | 66 (53.2) | 58 (46.8) | ||
| Smoking | ||||||
| Ever | 74 (73.3) | 27 (26.7) | 0.002 | 33 (32.7) | 68 (67.3) | 0.001 |
| Never | 89 (89.9) | 10 (10.1) | 56 (56.6) | 43 (43.4) | ||
| Tumor location | ||||||
| Left | 63 (84.0) | 12 (16.0) | 0.481 | 32 (42.7) | 43 (57.3) | 0.686 |
| Right | 100 (80.0) | 25 (20.0) | 57 (45.6) | 68 (54.4) | ||
| Pathological stage | ||||||
| I–II | 69 (79.3) | 18 (20.7) | 0.484 | 36 (41.4) | 51 (58.6) | 0.436 |
| III–IV | 94 (83.2) | 19 (16.8) | 53 (39.8) | 60 (60.2) | ||
Abbreviations: EGFR, epidermal growth factor receptor; TTF-1, thyroid transcription factor-1.