TABLE 2.
Relative expression of selected vascular maturation genes in FGF9-expressing renal tumors
Abundance of transcripts in 14-day-old renal tumors expressing FGF9 was determined by SYBR Green real-time PCR and expressed relative to that in control renal tumors.
| Gene | Fold-change | p value |
|---|---|---|
| mean ± S.D. | ||
| Pdgfb | 1.52 ± 0.30 | 0.037 |
| Pdgfd | 1.46 ± 0.20 | 0.014 |
| Pdgfra | 1.44 ± 0.26 | 0.043 |
| Pdgfrb | 1.57 ± 0.24 | 0.015 |
| Dll1 | 0.92 ± 0.39 | 0.817 |
| Dll4 | 1.18 ± 0.36 | 0.494 |
| Jag1 | 1.02 ± 0.26 | 0.941 |
| Jag2 | 1.19 ± 0.29 | 0.402 |
| Notch1 | 1.66 ± 0.29 | 0.031 |
| Notch2 | 1.61 ± 0.33 | 0.044 |
| Notch3 | 1.06 ± 0.43 | 0.886 |
| Notch4 | 1.03 ± 0.47 | 0.936 |
| Shh | 1.47 ± 0.25 | 0.049 |
| Ihh | 0.53 ± 0.14 | 0.087 |
| Sphk1 | 1.03 ± 0.34 | 0.931 |
| S1pr1 | 1.15 ± 0.31 | 0.470 |
| Apln | 1.03 ± 0.34 | 0.920 |
| Aplnr | 1.12 ± 0.48 | 0.697 |
| Efnb2 | 1.03 ± 0.38 | 0.939 |
| Ephb4 | 0.96 ± 0.17 | 0.774 |