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Analysis of CAP protein structure. a, overlay of the x-ray crystal structures of wild type CAP with cAMP (green) and wild type CAP with Sp-cAMPS (gold). b, close-up of the ligand-binding site of wild type CAP with cAMP showing the hydrogen-bonding network. c, close-up of the ligand-binding site of wild type CAP with Sp-cAMPS showing hydrogen-bonding network. d, overlay of ligand-binding sites of wild type CAP with cAMP and Sp-cAMPS.
