TABLE 1.

Crystallographic data collection and refinement statistics

Data collection
X-ray source	I04a
Wavelength (Å)	0.9687
Space group	P 1 21 1
Cell dimensions
a, b, c (Å)	45.7, 102.3, 54.3
α, β, γ (°)	90.0, 111.6, 90.0
Resolution (Å)b	50.5 (1.50–1.46)
Rmerge (%)b,c	5.5 (64.5)
I/σ(I)b	14.7 (2.3)
Completeness (%)b	99.6 (98.9)
Multiplicityb	4.5 (4.0)
Refinement
Resolution (Å)	1.46
No. measurements	358,197
No. unique	80,040
Rwork/Rfree	0.1871/0.2150
No. atoms
Protein	3126
Ligand/ion	129
Water	255
Average B-factor	30.889
Root mean square deviations
Bond lengths (Å)	0.0138
Bond angles (°)	1.8058
Protein Data Bank code	4R8H

^a Diamond Light Source.

^b Number in parentheses is for the last shell.

^c r = Σ(Abs(I − <I>)/Σ(I)).