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. 2015 Jun 12;307(8):705–720. doi: 10.1007/s00403-015-1575-x

Fig. 2.

Fig. 2

HD-OCT dermal ultrastructural and microvascular features of PD in women of three different age groups. Young women: a cross-sectional image with dark blue horizontal line indicating the Z value of the en face image. b Same cross-sectional image with epidermis edging (orange lines). Left side of the blue line is still corresponding to DEJ while right side of the blue line is already corresponding to the PD. c Corresponding en face image. Left side displays the DEJ and some artefacts (magenta arrows). Right side displays the superficial part of the PD. Thin, short and curled fibers form a randomly oriented feltwork (green circles). Disperse black dots align with these fibers (light blue arrow). Clusters of black dots (yellow circles) are noticed around the capillary loops (green arrows). The capillary bed of PD present as numerous homogenous distributed small round hyporeflective spaces (green arrows). Candle stick holder configuration of black dots is encircled in yellow on cross-sectional image. Middle aged women: d cross-sectional imaging with dark blue horizontal line indicating the Z value of the en face image. e Same cross-sectional image with epidermis edging (orange lines). Left side of the blue line is still corresponding to the DEJ. Right side of the blue line is already indicating the PD. The ET is thinner than in young adults. f Corresponding en face image. 2/3 of left side displays the DEJ with one artefact (magenta arrow). Right side displays the superficial part of the PD. Fibers are thicker, longer and straighter compared to young adults. Moreover, they become more aggregated and aligned in few directions (green circles). Disperse black dots condensed but still aligned with fibers (light blue arrows). Clusters of black dots increase in density and are progressively oriented in a more horizontal way (thin yellow circle on cross-sectional image). A reduction of the capillary area is observed (green arrows). Older aged women: g cross-sectional image with dark blue line indicating the Z value of the en face image. h Same cross-sectional image with epidermis edging (orange lines). At the left side of the image the blue line corresponds with lower PD while at the right side of the image blue line corresponds with middle part of PD. Epidermal thickness is thinner than in middle aged adults. i Fibers become more and more aggregated in a lace-like network (green circle). Clusters of black dots merge to form compact dark blotches. A further reduction of the density of the capillary bed (green arrows) is noticed resulting in an increase in lower capillary density. The top of the image corresponds with the upper part of the reticular dermis displaying a prominent sub-papillary plexus (magenta circle)