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. 2015 Jul 17;24(19):5655–5664. doi: 10.1093/hmg/ddv279

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© The Author 2015. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Locus-zoom plot for chromosome 13 locus. The plot shows the locus on chromosome 13 associated with normal hearing functions measured at 2 kHz, highlighting the top SNP rs78043697 and several other significant SNPs in the same region being in high linkage disequilibrium. The results plotted were obtained with a two-stage meta-analysis, focusing on Italian isolates first and then including the communities from the Silk Road. The y-axis shows −log₁₀ of the P-values obtained from the complete meta-analysis of the 2 kHz hearing threshold. The closest gene PCDH20 is shown along the x-axis.