Table 1.
Cross-sectional analysis of the genotypic and allelic frequencies of SIRT1 single nucleotide polymorphisms rs12778366 in the TRELOONG population
| SNP (no.) | Genotype no. (%) | Allele no. (%) | ||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| ≤ 85 y | > 85 y | χ2 statistics | ≤ 85 y | > 85 y | χ2 statistics | |||
| rs12778366 (n=586) | TT | 261 (80.1) | 201 (77.3) | χ2=0.72 | T | 583 (89.4) | 458 (88.1) | χ2=0.56 |
| TC | 61 (18.7) | 56 (21.5) | d.f.=2 | C | 69 (10.6) | 62 (11.9) | d.f.=1 | |
| CC | 4 (1.2) | 3 (1.2) | P=0.69 | P=0.45 | ||||
| rs12778366 dominant model (n=586) | TT | 261 (80.1) | 201 (77.3) | χ2=0.65 | ||||
| TC+CC | 65 (19.9) | 59 (22.7) | d.f.=1 | |||||
| P=0.41 | ||||||||
Abbreviations: no.; number; 85 y: 85 years of age; d.f, degree of freedom; P: P-value.