Immunostaining of cyclooxygenase-2 in the gastric mucosa with CSG (A), GA (B), IM (C), dysplasia (D) and gastric cancer (E). CSG showing strong expression in foveolar and glandular epithelium and weak expression in mononuclear inflam-matory cells, myofibroblasts, and endothelial cells in the lamina propria; GA showing strong expression in the atrophic glands of the gastric mucosa; IM showing strong expression in intestinal epithelium and goblet cells; and gastric cancer showing strong expression in cancer cells.