Table 3.
The pituitary-gonadal axis (on d 15) in the three experimental groups
| Healthy control rats (CO, n = 12) | Untreated cirrhotic rats (CI, n = 12) | IGF-1-treated cirrhotic rats (CI + IGF, n = 12) | |
| Total testosterone (ng/dL) | 62 ± 13 | 77 ± 17 | 64 ± 7 |
| Free testosterone (pg/mL) | 0.36 ± 0.09 | 0.36 ± 0.10 | 0.41 ± 0.05 |
| Estradiol (pg/mL) | 31 ± 2 | 33 ± 2 | 29 ± 1 |
| Estradiol/Total testosterone | 0.5 ± 0.1 | 0.5 ± 0.1 | 0.6 ± 0.1 |
| LH (ng/mL) | 4.8 ± 0.6 | 6.0 ± 0.5 | 3.8 ± 0.7d |
| FSH (ng/mL) | 22 ± 8 | 27 ± 1f | 26 ± 4b |
b
P < 0.01 CI + IGF vs CO group;
d
P < 0.01 CI + IGF vs CI group;
f
P < 0.001 CI vs CO group.