Table 1.

Plasma concentrations of TGF-β₁, TIMP-1 and MMP-1 during treatment with lamivudine (mean ± SE)

	Normal values	Time since treatment beginning (wk)
		0	24	48	72
TGF-β1 (ng/mL)	18.3 ± 1.6	29.6 ± 2.21	22.6 ± 1.22	21.9 ± 1.52	24.1 ± 2.4
TIMP-1 (ng/mL)	1102.0 ± 67	1578.0 ± 931	1235.0 ± 672	927.0 ± 502	1215.0 ± 982
MMP-1 (ng/mL)	11.9 ± 0.9	6.7 ± 0.71	8.3 ± 0.51	9.6 ± 0.51	9.7 ± 0.72

Statistical significance in comparison with

¹normal and

²baseline values.