Table 4.
Percentages of specific targets lysis by HLA-A2+ effec-tor CTLs induced by PBMCs from chronic hepatitis B patients with different peptide antigens (mean ± SD, n = 27)
| E/T ratios |
Percentage of specific cell lysis (%) |
||||
| Peptide1d | Peptide2d | Peptide3db | Irrelevant controla | Negative controls | |
| 12.5 | 18.7 ± 3.6 | 23.1 ± 4.9 | 30.2 ± 6.1 | 5.1 ± 0.8 | 4.3 ± 0.6 |
| 25 | 22.7 ± 4.1 | 28.6 ± 5.6 | 38.4 ± 7.4 | 4.5 ± 0.7 | 7.1 ± 1.0 |
| 50 | 31.3 ± 6.0 | 33.9 ± 6.5 | 52.7 ± 10.3 | 7.3 ± 1.1 | 7.7 ± 1.3 |
| 100 | 35.5 ± 5.7 | 39.1 ± 7.3 | 58.5 ± 15.9 | 9.5 ± 1.7 | 8.5 ± 1.5 |
a
P > 0.05 vs negative control,
b
P < 0.01 vs peptide1 and 2 groups,
d
P < 0.01 vs negative control.