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TMP-induced ISC response in T84 and Caco-2 cell lines. The concentration-response curve for TMP-induced response in T84 and Caco-2 cells, and each datum was obtained from at least 4 individual experiments. A: Values are mean ± SE of maximal ISC increase; B: Representative ISC recordings in response to apical addition of TMP (1 mmol/L) in T84 cells; C: Basolateral application of TMP (5 mmol/L) in Caco-2 cells.
