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Manometric samples from a normal individual (A) and a patient with achalasia (B). Figure A illustrates the normal peristaltic activity forwarding at cranio-caudal direction whereas figure B shows typical manometric findings of achalasia. Note the aperistalsis, weak and simultaneous contractions (mirror sign), and incomplete LES relaxation after swallow. Basal LES pressure is high (40 mmHg).
