Fig. 2.

Series of scatter plots examining the relationship between varying metrics of plaque strain in the internal carotid artery and total WMH lesion burden. The strain measurement is on the x-axis; strain measurements were log transformed to achieve normal distributions appropriate for linear regression analyses. WMH total lesion volume was adjusted for age, gender, BMI, treatment for hyperlipidemia (yes/no), hypertension, and stenosis percentage. The residualized WMH values after adjusting for these covariates is plotted on the y-axis. A positive association is seen, with increasing strain corresponding with an increasing amount of WMH. Relationships between WMH and A. maximum absolute axial strain, B. peak to peak axial strain, C. maximum absolute lateral strain, D. peak to peak lateral strain, E. maximum absolute shear strain and F. peak to peak shear strain.