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. 2015 Jun 24;309(6):F551–F558. doi: 10.1152/ajprenal.00076.2015

Fig. 1.

Fig. 1.

microRNA (miR)-150 deletion protects the kidney against myocardial infarction (MI)-induced acute kidney injury (AKI). A: description of MI surgery protocol. B: time course of serum creatinine rise after sham and MI surgery in wild-type (WT) mice. *P < 0.001 vs. corresponding time point in sham; n = 4–6. C: serum creatinine at 48 h after sham and MI surgery in WT and miR-150 knockout (KO) animals. *P < 0.05 vs. other groups; n = 4–6. D: RT-PCR analysis of inflammatory cytokine and kidney injury markers in WT and miR-150 KO animals. *P < 0.05 vs. other groups; n = 4. E: periodic acid Schiff (PAS)-stained section from sham and MI-operated WT and miR-150 KO animals showing no visible structural changes in the kidney with MI.