Table 2.
The arithmetic mean (AM), minimum (MIN) and maximum (MAX) faecal egg counts before (pre) and after (post) treatment for each treatment group on the 12 farms (GE01-12) in Germany. The number of animals in each treatment group (n) and the number of animals with a positive faecal egg count after treatment (n pos) are provided, along with the % larvae before and after treatment (Oo = Ostertagia ostertagi and C = Cooperia spp). The percentage (%) efficacy is provided calculated based on the arithmetic group mean, along with the lower (L95) and upper (U95) 95% confidence limits. The anthelmintic resistance status (Status) is provided as EFF (efficacious), confirmed anthelmintic resistance (CAR) or Inconclusive (INC).
| Farm | Treatment | Pre |
Post |
Efficacy |
Larvae pre |
Larvae post |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | AM | MIN | MAX | n pos | AM | MIN | MAX | % | L95 | U95 | Status | Oo | C | Oo | C | ||
| GE01 | MOX | 10 | 260 | 75 | 550 | 8 | 58 | 0 | 187.5 | 76.8 | 56.9 | 90.4 | CAR | 44 | 56 | 3 | 97 |
| IVM | 10 | 258 | 62.5 | 475 | 9 | 55 | 0 | 150 | 78.3 | 63.3 | 88.4 | CAR | 3 | 97 | |||
| GE02 | MOX | 10 | 75 | 25 | 187.5 | 2 | 3 | 0 | 12.5 | 96.5 | 91.3 | 100.0 | EFF | 100 | 0 | 100 | 0 |
| IVM | 10 | 75 | 37.5 | 175 | 2 | 4 | 0 | 25 | 94.9 | 86.8 | 100.0 | INC | 90 | 10 | |||
| GE03 | MOX | 10 | 133 | 12.5 | 625 | 3 | 9 | 0 | 62.5 | 92.0 | 75.0 | 100.0 | INC | 77 | 22 | 0 | 100 |
| IVM | 10 | 109 | 12.5 | 475 | 1 | 1 | 0 | 12.5 | 98.7 | 94.6 | 100.0 | EFF | NL | ||||
| GE04 | MOX | 10 | 89 | 25 | 325 | 1 | 4 | 0 | 37.5 | 95.5 | 82.4 | 100.0 | INC | 40 | 60 | 0 | 100 |
| IVM | 10 | 129 | 25 | 587.5 | 0 | 0 | 0 | 0 | 100.0 | 100.0 | 100.0 | EFF | 0 | 100 | |||
| GE05 | MOX | 10 | 836 | 62.5 | 5587.5 | 6 | 15 | 0 | 37.5 | 97.3 | 91.1 | 99.5 | EFF | 20 | 80 | 2 | 95 |
| IVM | 10 | 465 | 37.5 | 2212.5 | 5 | 18 | 0 | 75 | 95.2 | 85.7 | 99.1 | INC | 2 | 98 | |||
| GE06 | MOX | 10 | 106 | 12.5 | 387.5 | 5 | 23 | 0 | 125 | 77.2 | 37.3 | 96.7 | INC | 21 | 79 | 5 | 95 |
| IVM | 10 | 96 | 12.5 | 262.5 | 2 | 4 | 0 | 25 | 95.7 | 87.3 | 100.0 | INC | 5 | 95 | |||
| GE07 | MOX | 8 | 78 | 12.5 | 225 | 4 | 8 | 0 | 25 | 89.0 | 76.5 | 97.4 | INC | 4 | 95 | 6 | 94 |
| IVM | 7 | 75 | 25 | 200 | 3 | 7 | 0 | 25 | 89.9 | 73.9 | 98.4 | INC | 30 | 67 | |||
| GE08 | MOX | 10 | 69 | 25 | 150 | 3 | 4 | 0 | 12.5 | 94.4 | 88.0 | 98.6 | INC | 91 | 6 | NL | |
| IVM | 10 | 66 | 12.5 | 137.5 | 2 | 20 | 0 | 175 | 69.6 | 8.3 | 100.0 | INC | 24 | 76 | |||
| GE09 | MOX | 10 | 64 | 12.5 | 212.5 | 4 | 9 | 0 | 25 | 85.0 | 64.7 | 97.3 | INC | 43 | 57 | NL | |
| IVM | 10 | 60 | 12.5 | 162.5 | 2 | 3 | 0 | 12.5 | 95.7 | 88.6 | 100.0 | INC | 10 | 90 | |||
| GE10 | MOX | 10 | 101 | 37.5 | 237.5 | 2 | 3 | 0 | 12.5 | 97.5 | 93.8 | 100.0 | EFF | 31 | 69 | 13 | 87 |
| IVM | 10 | 74 | 12.5 | 175 | 3 | 5 | 0 | 25 | 92.8 | 83.3 | 98.6 | INC | NL | ||||
| GE11 | MOX | 10 | 103 | 50 | 175 | 4 | 13 | 0 | 50 | 87.5 | 75.0 | 97.1 | INC | 44 | 56 | 29 | 71 |
| IVM | 10 | 114 | 50 | 250 | 3 | 5 | 0 | 25 | 95.5 | 89.6 | 100.0 | INC | 9 | 91 | |||
| GE12 | MOX | 10 | 86 | 37.5 | 200 | 3 | 4 | 0 | 12.5 | 95.4 | 90.0 | 99.2 | EFF | 35 | 64 | 13 | 88 |
| IVM | 10 | 129 | 37.5 | 650 | 5 | 66 | 0 | 450 | 36.6 | 0.00 | 95.3 | INC | 20 | 80 | |||
NL = no larvae were found in the coproculture. MOX = moxidectin injectable. IVM = ivermectin injectable.