Table 3.
The arithmetic mean (AM), minimum (MIN) and maximum (MAX) faecal egg counts before (pre) and after (post) treatment for each treatment group on the 10 farms (IT01-10) in Italy. The number of animals in each treatment group (n) and the number of animals with a positive faecal egg count after treatment (n pos) are provided, along with the % larvae before and after treatment (Hae = Haemonchus spp. and C = Cooperia spp). The percentage (%) efficacy calculated based on the arithmetic group mean is provided, along with the lower (L95) and upper (U95) 95% confidence limits. The anthelmintic resistance status (Status) is provided as EFF (efficacious), confirmed anthelmintic resistance (CAR) or Inconclusive (INC).
| Farm | Treatment | Pre |
Post |
Efficacy |
Larvae pre |
Larvae post |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | AM | MIN | MAX | n pos | AM | MIN | MAX | % | L95 | U95 | Status | Hae | C | Hae | C | ||
| IT01 | MOX | 10 | 63 | 25 | 125 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 78a | 18a | ||
| IVM | 9 | 97 | 50 | 400 | 3 | 19 | 0 | 100 | 77.1 | 36.3 | 100.0 | INC | 100 | 0 | |||
| IT02 | MOX | 9 | 111 | 25 | 400 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 100 | 0 | ||
| IVM | 9 | 131 | 25 | 450 | 2 | 6 | 0 | 25 | 95.4 | 87.1 | 100.0 | INC | 100 | 0 | |||
| IT03 | MOX | 6 | 42 | 25 | 75 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 100 | 0 | ||
| IVM | 8 | 41 | 25 | 100 | 1 | 6 | 0 | 50 | 84.6 | 50.0 | 100.0 | INC | 100 | 0 | |||
| IT04 | MOX | 6 | 42 | 25 | 75 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 100 | 0 | ND | |
| IVM | 8 | 50 | 25 | 200 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | |||||
| IT05 | MOX | 7 | 64 | 25 | 225 | 1 | 4 | 0 | 25 | 93.4 | 71.4 | 100.0 | INC | 100 | 0 | NL | |
| IVM | 7 | 39 | 25 | 100 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | |||||
| IT06 | MOX | 10 | 38 | 25 | 62.5 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 100 | 0 | ND | |
| IVM | 10 | 40 | 25 | 112.5 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | |||||
| IT07 | MOX | 10 | 49 | 25 | 125 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 100 | 0 | ND | |
| IVM | 10 | 46 | 25 | 100 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | |||||
| IT08 | MOX | 10 | 46 | 25 | 87.5 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 100 | 0 | ND | |
| IVM | 10 | 48 | 25 | 87.5 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | |||||
| IT09 | MOX | 10 | 38 | 25 | 75 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 100 | 0 | ND | |
| IVM | 10 | 35 | 25 | 50 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | |||||
| IT10 | MOX | 10 | 46 | 25 | 137.5 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 100 | 0 | ND | |
| IVM | 10 | 45 | 25 | 112.5 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | |||||
ND = for those groups with high efficacy no copro-culture was performed. NL = no larvae were found in the coproculture.
MOX = moxidectin injectable. IVM = ivermectin injectable.
On IT01, Oesophagostomum (4%) was identified as well pre-treatment.