Table 4.
The arithmetic mean (AM), minimum (MIN) and maximum (MAX) faecal egg counts before (pre) and after (post) treatment for each treatment group on the 10 farms (UK02 and UK06-14) in the UK. The number of animals in each treatment group (n) and the number of animals with a positive faecal egg count after treatment (n pos) are provided, along with the % larvae before and after treatment (Oo = Ostertagia ostertagi and C = Cooperia spp). The percentage (%) efficacy calculated based on the arithmetic group mean is provided, along with the lower (L95) and upper (U95) 95% confidence limits. The anthelmintic resistance status (Status) is provided as EFF (efficacious), confirmed anthelmintic resistance (CAR) or Inconclusive (INC).
| Farm | Treatment | Pre |
Post |
Efficacy |
Larvae pre |
Larvae post |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | AM | MIN | MAX | n pos | AM | MIN | MAX | % | L95 | U95 | Status | Oo | C | Oo | C | ||
| UK02 | MOX | 10 | 353 | 37.5 | 800 | 10 | 35 | 12.5 | 125 | 89.8 | 80.8 | 95.3 | INC | 10 | 47 | 17 | 68 |
| IVM | 10 | 320 | 12.5 | 862.5 | 10 | 61 | 12.5 | 237.5 | 79.3 | 55.6 | 92.5 | CAR | 0 | 99 | |||
| UK06 | MOX | 10 | 243 | 162.5 | 412.5 | 6 | 21 | 0 | 62.5 | 91.2 | 84.5 | 96.9 | INC | NL | 94 | 6 | |
| IVM | 10 | 234 | 150 | 350 | 6 | 13 | 0 | 50 | 94.6 | 90.6 | 98.0 | INC | 100 | 0 | |||
| UK07 | MOX | 10 | 254 | 87.5 | 762.5 | 2 | 9 | 0 | 75 | 96.4 | 89.6 | 100.0 | INC | 41 | 52 | 0 | 100 |
| IVM | 10 | 223 | 75 | 400 | 2 | 3 | 0 | 12.5 | 98.8 | 97.0 | 100.0 | EFF | 0 | 90 | |||
| UK08 | MOX | 10 | 170 | 62.5 | 625 | 7 | 14 | 0 | 25 | 91.2 | 83.9 | 96.0 | INC | 57 | 40 | 16 | 84 |
| IVM | 10 | 126 | 62.5 | 337.5 | 5 | 29 | 0 | 187.5 | 76.8 | 41.3 | 96.3 | INC | 6 | 94 | |||
| UK09 | MOX | 10 | 95 | 50 | 175 | 0 | 0 | 0 | 0 | 100.0 | 100.0 | 100.0 | EFF | 69 | 17 | NL | |
| IVM | 10 | 105 | 50 | 250 | 0 | 0 | 0 | 0 | 100.0 | 100.0 | 100.0 | EFF | |||||
| UK10 | MOX | 10 | 216 | 75 | 437.5 | 2 | 3 | 0 | 12.5 | 98.8 | 97.1 | 100.0 | EFF | 21 | 55 | 0 | 100 |
| IVM | 10 | 303 | 137.5 | 937.5 | 1 | 1 | 0 | 12.5 | 99.6 | 98.6 | 100.0 | EFF | 0 | 100 | |||
| UK11 | MOX | 9 | 722 | 212.5 | 3075 | 4 | 18 | 0 | 50 | 97.1 | 92.1 | 99.5 | EFF | 21 | 78 | 32 | 68 |
| IVM | 9 | 546 | 187.5 | 2162.5 | 6 | 63 | 0 | 175 | 86.8 | 67.4 | 97.2 | INC | 29 | 70 | |||
| UK12 | MOX | 10 | 391 | 125 | 925 | 6 | 21 | 0 | 137.5 | 94.5 | 86.2 | 98.8 | INC | 56 | 44 | 10 | 90 |
| IVM | 10 | 388 | 125 | 687.5 | 7 | 56 | 0 | 175 | 85.0 | 72.7 | 95.0 | CAR | 18 | 82 | |||
| UK13 | MOX | 10 | 299 | 150 | 737.5 | 5 | 11 | 0 | 62.5 | 96.2 | 91.3 | 99.1 | EFF | 26 | 74 | 21 | 79 |
| IVM | 9 | 351 | 137.5 | 1137.5 | 5 | 63 | 0 | 450 | 80.7 | 44.4 | 98.4 | INC | 38 | 61 | |||
| UK14 | MOX | 10 | 149 | 62.5 | 587.5 | 10 | 18 | 12.5 | 50 | 87.1 | 75.3 | 94.1 | CAR | 40 | 60 | 27 | 67 |
| IVM | 10 | 113 | 50 | 262.5 | 10 | 60 | 12.5 | 287.5 | 46.4 | −12.5 | 83.3 | CAR | 0 | 100 | |||
NL = no larvae were found in the coproculture. MOX = moxidectin injectable. IVM = ivermectin injectable.