Table 5.
The arithmetic mean (AM), minimum (MIN) and maximum (MAX) faecal egg counts before (pre) and after (post) treatment for each treatment group on the 8 farms (FR01-12) in France. The number of animals in each treatment group (n) and the number of animals with a positive faecal egg count after treatment (n pos) are provided, along with the % larvae before and after treatment (Oo = Ostertagia ostertagi and C = Cooperia spp). The percentage (%) efficacy calculated based on the arithmetic group mean is provided, along with the lower (L95) and upper (U95) 95% confidence limits. The anthelmintic resistance status (Status) is provided as EFF (efficacious), confirmed anthelmintic resistance (CAR) or Inconclusive (INC).
| Farm | Treatment | Pre |
Post |
Bootstrap |
Larvae pre |
Larvae post |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | AM | MIN | MAX | n pos | AM | MIN | MAX | % | L95 | U95 | Status | Oo | C | Oo | C | ||
| FR01 | MOX | 9 | 40 | 15 | 90 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 91 | 9 | ND | |
| IVM | 9 | 57 | 15 | 165 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | ND | ||||
| FR04 | MOX | 7 | 41 | 15 | 75 | 2 | 9 | 0 | 45 | 77.5 | 37.5 | 100.0 | INC | 76 | 24 | NL | |
| IVM | 9 | 38 | 15 | 75 | 4 | 12 | 0 | 45 | 68.3 | 35.0 | 95.0 | INC | |||||
| FR05 | MOX | 8 | 168 | 15 | 465 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 0 | 100 | ND | |
| IVM | 7 | 216 | 15 | 735 | 2 | 9 | 0 | 45 | 95.2 | 82.5 | 100.0 | INC | ND | ||||
| FR06 | MOX | 9 | 110 | 15 | 315 | 6 | 47 | 0 | 135 | 52.6 | −12.1 | 86.1 | CAR | 6 | 94 | 0 | 100 |
| IVM | 9 | 138 | 15 | 600 | 3 | 37 | 0 | 210 | 68.5 | 2.5 | 98.1 | INC | 0 | 100 | |||
| FR08 | MOX | 9 | 137 | 30 | 420 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | 12 | 88 | ND | |
| IVM | 9 | 170 | 30 | 465 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | ND | ||||
| FR09 | MOX | 10 | 74 | 15 | 165 | 6 | 21 | 0 | 45 | 70.1 | 43.9 | 87.7 | CAR | NL | 0 | 100 | |
| IVM | 10 | 176 | 15 | 1125 | 1 | 2 | 0 | 15 | 98.8 | 94.3 | 100.0 | EFF | 6 | 94 | |||
| FR11 | MOX | 9 | 75 | 15 | 210 | 2 | 5 | 0 | 30 | 92.7 | 78.9 | 100.0 | INC | 5 | 95 | NL | |
| IVM | 8 | 84 | 15 | 240 | 0 | 0 | 0 | 0 | 100 | 100.0 | 100.0 | EFF | |||||
| FR12 | MOX | 10 | 167 | 60 | 345 | 8 | 50 | 0 | 195 | 68.8 | 39.6 | 88.7 | CAR | 0 | 100 | 0 | 100 |
| IVM | 10 | 161 | 75 | 345 | 5 | 36 | 0 | 120 | 77.3 | 57.6 | 94.1 | CAR | 0 | 100 | |||
ND = for those groups with high efficacy no copro-culture was performed. NL = no larvae were found in coproculture. MOX = moxidectin injectable. IVM = ivermectin injectable.