Table 2.

Effect of pendrin gene ablation on serum electrolytes and aldosterone and plasma renin concentration in mice consuming a KCl-rich diet

	Wild Type	Pendrin Null
Na+ (meq/l)	134 ± 6.2 (n = 4)	138 ± 0.3 (n = 3)
K+ (meq/l)	3.7 ± 0.5 (n = 4)	5.6 ± 0.5 (n = 3)*
Cl− (meq/l)	97 ± 3 (n = 4)	97 ± 0 (n = 3)
Aldosterone (nM)	49.4 ± 5.7 (n = 7)	52.6 ± 6.9 (n = 6)
Renin concentration (μg Ang I/ml/h)	1.02 ± 0.15 (n = 5)	2.97 ± 1.14 (n = 6)
Aldosterone/renin ratio (nM/μg Ang I/ml/h)	43.1 ± 1.4 (n = 5)	24.1 ± 4.6 (n = 6)*

^*P < 0.05.