Table 2.
Demographic, clinical and genotypic characteristics of the EHDN Huntington’s disease cohort
| H1/H1 | H1/H2 | H2/H2 | F/ChiSq | Pa | |
|---|---|---|---|---|---|
| n | 283 | 161 | 29 | ||
| Ageb | 49.41(12.88) | 50.55 (10.98) | 48.07 (12.27) | 0.727 | 0.484 |
| CAG repeat length | 44.45 (4.74) | 43.76 (3.12) | 44.86 (5.11) | 1.646 | 0.194 |
| Years since disease onsetb | 7.29 (5.01) | 7.26 (4.65) | 5.33 (4.03) | 2.210 | 0.111 |
| Interval between visits (years) | 1.88 (1.16) | 1.97 (1.14) | 1.83 (0.99) | 0.430 | 0.691 |
| Gender(F:M) | 137:146 | 83:78 | 11:18 | 1.876 | 0.391 |
| UHDRS Motor scoreb | 28.11 (15.71) | 28.62 (16.38) | 26.41 (20.31) | 0.231 | 0.794 |
| UHDRS Functional scoreb | 9.31 (2.94) | 9.27 (2.89) | 9.52 (3.57) | 0.087 | 0.916 |
| Cognitive scoreb | 176.88 (60.19) | 178.31 (63.20) | 185.76 (79.23) | 0.271 | 0.763 |
Group means are shown with standard deviations in parenthesis. UHDRS = Unified Huntington's Disease Rating Scale; M = Male; F = Female.
aDerived from independent one-way ANOVA or χ2 tests for categorical data.
bAt first visit.