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. 2015 Jul 7;109(1):85–94. doi: 10.1016/j.bpj.2015.04.042

Figure 5.

Figure 5

CFTR macro- and microdynamics and distribution on the plasma membrane are cholesterol dependent. (a) Both Dmacro and Dmicro of CFTR increased significantly after cholesterol depletion from the membrane (+COase) and decreased significantly after cholesterol augmentation (+CEase). (b) Gray bars indicate the unconfined population fraction, fmacro, increased by cholesterol loss (+COase) and decreased after cholesterol insertion (+CEase). Black bars indicate the confined population fraction of CFTR, fmicro, decreased significantly after COase and increased significantly after CEase. Error bars indicate the mean ± SE.