TABLE 1.
Details of HCV recombinants proposed in the literature
| Genotype or subtype | Location of estimated recombination breakpoint(s) |
Source | |
|---|---|---|---|
| Gene(s) | Nucleotide position(s)a | ||
| 1a/1c | E1, E2 | 1407, 2050 | 10 |
| 1a/1c | Core, E1, E2, NS2, NS3 | 801, 1261, 2181, 3041, 3781 | 4 |
| 1b/1a | NS5B | 8320 | 47 |
| 1b/1a | Core | 387 | 48 |
| 2/5b | NS2/NS3 | 3420–3440 | 49 |
| 2b/1a | NS2/NS3 | 3405–3416 | 50 |
| 2b/1b | NS2/NS3 | 3443 | 51 |
| 2b/1b | NS2/NS3 | 3399 | 52 |
| 2b/1b | NS2 | 3298–3305 | 9 |
| 2b/6w | NS2/NS3 | 3429 | 53 |
| 2k/1b | NS2/NS3 | 3175 | 6 |
| 4d/4a | Between E2 and NS5A | Unknown | 54 |
| 6a/6o | NS5B | 8345 | 11 |
| 6e/6h | NS5B | 8356 | 11 |
| 6e/6o | NS5B | 8358 | 11 |
| 6n/6o | NS5B | 8372 | 11 |
a
Nucleotide positions are relative to isolate H77.
b
Entries in bold are intergenotypic recombinants.