Clustering dendrogram of the 48 M. pneumoniae-positive Japanese clinical specimens based on SNP profiles at eight genomic loci. The dendrogram was constructed using the categorical coefficient and UPMGA clustering method (BioNumerics v.7.1). The MLVA profiles of MLVA-5 types 28, 64, 65, and 66 are 64573, 74473, 43262, and 24571, respectively. R, presence of macrolide resistance-associated mutation (A2058G or A2059G); WT, wild type; ND, not determined.