Table 1.

Simulation details

System	PDB ID	Notes	Simulation Time (ns)
Dark opsin	1U19	retinal removed	1 $\times \approx$ 3,000, 5 $\times \approx$ 4,000
Opsin	3CAP		3 $\times \approx$ 4,000, 3 $\times \approx$ 4,200
Meta-I	Meta-I	(from 45)	6 $\times \approx$ 4,800
Meta-II	3PXO		3 $\times \approx$ 4,000, 3 $\times \approx$ 4,200
		Total	$\approx$ 101,000 ns

An exhaustive list is available in Table S1.