Table 2.
The radioprotective effect of indralin and mexamine injected IM into dogs 5 min before γ-irradiation (47)
| Groups | Dose (Gy) | Dose rate (Gy/min) | Dose (mg/kg) | n | 60-day Survival (%) | MLS, (days) |
|---|---|---|---|---|---|---|
| Control | 3.8 | 2.3–2.8 | – | 14 | 14.3 | 17.0 |
| Indralin | 3.8 | 2.3–2.8 | 30.0 | 12 | 100.0* | – |
| 10.0 | 15 | 86.7* | 18.0 | |||
| 5.0 | 11 | 90.9* | 20.0 | |||
| Mexamine | 3.8 | 2.3–2.8 | 30.0 | 7 | 14.3 | 17.2 |
| 10.0 | 7 | 0 | 16.4 | |||
| 5.0 | 5 | 20.0 | 17.3 | |||
| Control | 4.0 | 0.1–0.11 | – | 27 | 14.8 | 17.3 |
| Indralin | 4.0 | 0.1–0.11 | 30.0 | 11 | 90.9* | 16.0 |
| Mexamine | 4.0 | 0.1–0.11 | 30.0 | 8 | 12.5 | 17.6 |
Statistically significant (P < 0.05 by two-tail Fisher exact test) difference between indralin and mexamine groups is indicated with an asterisk. MLS = mean of life span of deceased animals, n = number of animals.