Table 2.
Part of the previously reported up-regulated genes in activation of HSC
| GenBank accession number | Gene name | Ratio (Cy5/Cy3) | Potential gene function |
| M73741 | Alpha-B2-crystallin, complete cds | 155.619 | Small heat shock protein gene, an early marker for HSC activation |
| X52046 | Procollagen, type III, alpha 1 | 119.092 | Extracellular matrix (ECM), over- expressed in hepatic fibrosis |
| M18194 | Fibronectin mRNA | 29.958 | ECM, over expressed in hepatic fibrosis |
| J02870 | Laminin receptor mRNA | 6.62 | ECM receptor (integrin), cell adhesion |
| L08115 | CD9 antigen | 6.094 | Cell membrane glycoprotein, involved in cell activation and adhesion |
| U16163 | Prolyl 4-hydroxylase alpha (II) - subunit mRNA, complete cds | 4.555 | An enzyme which is essential for the collagen synthesis in HSC |
| X62622 | TIMP-2 mRNA for tissue inhibitor of metalloproteinase, type 2 | 3.732 | Inhibition for ECM degradation |
| X04017 | mRNA for cysteine-rich glycoprotein SPARC | 3.435 | Regulation of cell shape, adhesion, migration and proliferation |
| AF070470 | SPARC-related protein (SRG) mRNA, complete cds | 3.181 | Regulation of cell shape, adhesion, migration |
| M21495 | Cytoskeletal gamma-actin mRNA, | 3.092 | Relate skeleton structure of cell |
| AF188297 | TGF-beta receptor binding protein (Trip1) mRNA, complete cds | 2.976 | TGF-beta mediated signaling pathway |
| AJ245923 | alpha-tubulin 8 (Tuba 8 gene) mRNA | 2.901 | Relate skeleton structure of cell |
| AF053454 | Tetraspan TM4SF (Tspan-6) mRNA complete cds, | 2.896 | Cell development, differentiation, motility |
| AF013262 | Lumican gene, complete cds | 2.862 | Small, leucine-rich proteoglycan which involves in the regulation of collagen figril assembly |
| L02526 | Protein kinase (MEK) mRNA | 2.714 | Signaling molecule in MAPK family |
| Y00769 | mRNA for integrin beta subunit | 2.521 | Signaling molecular in cell adhesion, proliferation and migration |