Right liver lobe volume × platelet count/spleen volume is better than platelet count, spleen volume/platelet count or spleen volume index/platelet count for distinguishing cirrhotic patients from healthy participants (A), Child-Pugh class A of cirrhosis from B, A from C, and B from C; and SV/PLT is better than PLT, RVPS or SI/PLT for identifying esophageal varices (E). RVPS: Right liver lobe volume × platelet count/spleen volume; PLT: Platelet count; SV/PLT: Spleen volume/platelet count; SI/PLT: Spleen volume index/platelet count.