Table 1.
The main clinical characteristics of healthy volunteers and cirrhotic patients with different modified Child-Pugh classes
| Variable | Healthy volunteers |
Cirrhotic patients (n = 205) |
P value | ||
| (n = 40) | Class A (n = 47) | Class B (n = 95) | Class C (n = 63) | ||
| Gender (M/F) | 24/16 | 24/23 | 60/35 | 43/20 | 0.816 |
| Age (yr) | 51.50 ± 2.31 | 58.13 ± 1.83 | 55.99 ± 1.18 | 54.38 ± 1.63 | 0.056 |
| Esophageal varices | Not appear | 17.02% (8/47) | 45.26% (43/95)1 | 58.73% (37/63)1 | < 0.001a |
| PLT (109/L) | 249.70 ± 5.71 | 178.29 ± 12.77 | 137.67 ± 22.171 | 82.44 ± 21.1412 | < 0.001a |
| SV/PLT | 0.56 ± 0.03 | 1.98 ± 0.25 | 5.23 ± 1.051 | 29.50 ± 13.5512 | < 0.001a |
| SI/PLT | 1.15 ± 0.06 | 4.07 ± 0.49 | 11.77 ± 2.081 | 67.39 ± 24.9112 | < 0.001a |
| RVPS | 1898.72 ± 138.12 | 686.34 ± 121.37 | 359.99 ± 41.371 | 80.06 ± 10.1012 | < 0.001a |
1
Different from Child-Pugh class A;
2
Different from Child-Pugh class B, and all the comparisons denote significance after Bonferroni correction (P < 0.05).
a
P value shows the difference between cirrhotic patients and healthy volunteers. BMI: Body mass index; SV: Spleen volume; SI: Spleen volumetric index; PLT: Platelet count; RV: Right liver lobe volume; RVPS: RV × PLT/SV; M: Male; F: Female.