Table 1.

Prognostic factors in relapsed acute lymphoblastic leukemia

Poor prognostic factors for CR

Albumin level < 3 g/L*

Duration of first CR < 36 months*

Hemoglobin level < 10 g/dL

Platelet count ≤ 50 × 109/L*

Bone marrow blasts > 50%

Peripheral blood blasts ≥ 1%

Poor prognostic factors for survival

Albumin level < 3 g/L*

Duration of first CR < 36 months*

Hemoglobin level < 10 g/dL

Platelet count ≤ 50 × 109/L*

Bone marrow blasts > 50%*

Peripheral blood blasts ≥ 1%

White blood cell count > 20 × 109/L

^*Independent prognostic factors identified by multivariate analysis. All prognostic factors listed significantly reduced the rate of CR and survival.

CR—complete response.

(Adapted from O’Brien et al. [7••].)