Table 1.
Parameter | Unit | Dmt1flox/flox | Dmt1liv/liv | n | P |
---|---|---|---|---|---|
Hemoglobin | g/dL | 15.30 ± 0.33 | 15.18 ± 0.47 | 6 | 0.843 |
Plasma iron | µg/dL | 270.3 ± 17.72 | 283.5 ± 14.44 | 6 | 0.575 |
TIBC | µg/dL | 372.6 ± 15.01 | 375.0 ± 27.72 | 4–5 | 0.938 |
Transferrin saturation | % | 72.36 ± 4.25 | 73.88 ± 3.69 | 4–5 | 0.802 |
Hepatic iron | µg Fe/g | 796.7 ± 65.08 | 885.0 ± 12.66 | 3 | 0.254 |
Hepatic non-heme iron | µg Fe/g | 132.1 ± 22.24 | 125.9 ± 26.24 | 6 | 0.861 |
TIBC, total iron-binding capacity. Hepatic iron (heme and non-heme) levels were determined by ICP-MS, and are reported as µg Fe/g of tissue dry weight. Hepatic non-heme iron levels were measured colorimetrically and are reported as µg Fe/g of tissue wet weight. Values are means ± SE. Measurements were at 8 weeks of age. P values were obtained by using Student’s t test.