Figure 1A) Relative Allele Frequency Distribution of SCA2 Repeats in ET patients and Controls: A) All patients and controls (see Table 1 for demographic and clinical characteristics), B) Stratified by gender, 156 male ET patients vs. 125 male controls (mean age at tremor onset in ET cases=43.93 ± 21.88; 150 non-Hispanic white ET patients vs. 110 non-Hispanic white controls; 2 non-Hispanic black ET patients vs. 5 non- Hispanic black controls; 2 Hispanic ET patients vs. 5 Hispanic controls; 51 non-Hispanic white-AJ ET patients vs. 23 non-Hispanic white-AJ controls) and 167 female ET patients vs. 174 female controls mean age at tremor onset in ET patients=44.53 ± 21.92; 153 non-Hispanic white ET patients vs. 147 non-Hispanic white controls; 5 non-Hispanic black ET patients vs. 12 non-Hispanic black controls; 6 Hispanic ET patients vs. 7 Hispanic controls; 72 non-Hispanic white-AJ ET patients vs. 34 non-Hispanic white-AJ controls). C) Stratified by non-Hispanic white ethnicity, 303 ET patients vs. 257 controls (Mean age at tremor onset in ET patients= 44.06±22.07; 150 male ET cases vs. 110 male controls). D) Stratified by non-Hispanic white AJ ancestry, 123 ET cases vs. 57 controls (Mean age at tremor onset in ET patients= 47.38±21.88; 51 male ET cases vs. 23 male controls.
Figure 1B) Relative Allele Frequency Distribution of Repeats in SCA8 in ET patients and controls: A) All patients and controls (see Table 1 for demographic and clinical characteristics), B) Stratified by gender, 156 male ET patients vs. 125 male controls, Stratified by non-Hispanic white ethnicity, 303 ET patients vs. 257 controls and D) Stratified by non-Hispanic white AJ ancestry, 123 ET cases vs. 57 controls. The demographic and clinical characteristics of ET patients and controls within each strata is described in the legend for Figure 1A.