. 2015 Jan 15;52(10):6194–6205. doi: 10.1007/s13197-014-1672-4

Table 2.

The viability of HepG2 cell treated with Nile tilapia protein hydrolysates and Sephadex G-25 fractions in the absence and presence of oxidative stressors

Samples	Concentrations (mg/ml)	Cell viability (%)
Samples	Concentrations (mg/ml)	without oxidative stressors	H₂O₂	AAPH
HA	0.5	105.94 ± 0.33^{*,†,defghij}	98.02 ± 3.24^cde	93.05 ± 2.17^bcd
	1	103.38 ± 3.55^defghi	94.80 ± 2.82^def	92.68 ± 0.77^bcdefgh
	2	102.31 ± 4.91^fghjkl	92.61 ± 5.00^ef	89.63 ± 2.95^gh
FHA	0.5	107.42 ± 1.34^defghij	93.06 ± 1.31^ef	89.49 ± 2.83^h
	1	111.18 ± 0.99^bcde	96.93 ± 5.22^def	93.59 ± 2.25^bcd
	2	111.04 ± 2.70^bcde	97.36 ± 4.15^cdef	94.34 ± 1.39^bc
T+HA	0.5	100.09 ± 6.05^def	95.65 ± 1.04^def	93.42 ± 1.38^bcd
	1	102.65 ± 3.34^efghij	95.55 ± 3.46^def	94.77 ± 1.69^b
	2	102.24 ± 3.65^hijkl	95.38 ± 3.29^def	89.88 ± 3.21^fgh
T+FHA	0.5	105.44 ± 2.85^fghijk	94.74 ± 5.35^def	90.86 ± 3.57^defgh
	1	111.58 ± 2.70^bcd	95.94 ± 4.94^def	93.15 ± 1.56^bcd
	2	108.21 ± 6.67^dfgh	95.18 ± 3.42^def	93.63 ± 3.06^b
HAPa	0.5	107.42 ± 1.27^ijk	95.84 ± 1.27^def	89.59 ± 0.89^gh
	1	107.79 ± 1.61^ghijkl	97.14 ± 2.86^def	90.73 ± 2.51^efgh
	2	104.77 ± 2.40^efghijk	91.58 ± 3.48^f	91.10 ± 1.83^cdefgh
FHAPa	0.5	108.81 ± 1.73^defg	99.98 ± 4.17^cde	91.49 ± 1.29^bcdefgh
	1	116.03 ± 0.67^ac	107.64 ± 1.98^ab	91.74 ± .0.92^bcdefgh
	2	117.08 ± 1.11^a	111.40 ± 1.96^a	93.03 ± 1.12^bcd
T+HAPa	0.5	103.09 ± 0.78^jkl	102.97 ± 4.13^bc	89.91 ± 2.86^cd
	1	105.98 ± 0.11^ijkl	96.70 ± 3.39^def	94.19 ± 1.43^bcd
	2	108.96 ± 0.20^kl	96.92 ± 5.21^def	92.86 ± 1.19^bd
T+FHAPa	0.5	109.36 ± 0.27^de	98.06 ± 4.99^cd	93.00 ± 1.56^bcd
	1	116.34 ± 1.74^ab	106.63 ± 2.77^ab	94.34 ± 1.31^bc
	2	117.98 ± 0.05^a	109.64 ± 1.97^a	94.29 ± 1.31^bc
T		105.43 ± 4.39^fghijk	93.05 ± 2.00^ef	91.57 ± 1.28^bcdefgh
Control	–	100.00 ± 0.00^l	100.00 ± 1.97^cd	100.00 ± 0.95^a
Control damage	–		58.08 ± 1.65^g	48.14 ± 0.52ⁱ

^†Value are given as mean ± SD

^* Different superscripts in the same column indicate the significant differences (P<0.05).

HA Hydrolysate prepared using Alcalase

FHA Sephadex G-25 fraction of HA

HAPa Hydrolysate prepared using Alcalase, followed by papain

FHAPa Sephadex G-25 fraction of HAPa

T Trolox

Control Without antioxidant, hydrolysates or fractions

Control damage Including oxidative stressor (without antioxidant, hydrolysates or fractions)