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. 2015 Sep 9;10:1863–1881. doi: 10.2147/COPD.S87082

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© 2015 Huisman et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Forest plot for (A) mean trough FEV₁, (B) mean SGRQ total scores, (C) mean TDI focal scores, and (D) mean rescue medication use of UMEC 55 μg/VI 22 μg versus comparators at 24 weeks.

Notes: Dotted lines included in panels (A–C) indicate the MCIDs versus placebo if these have been defined: these have been included in the graph for reference purpose only. The values shown on the right of each figure represent mean (95% CI).

Abbreviations: CFB, change from baseline; FEV₁, forced expiratory volume in 1 second; FOR, formoterol; MCID, minimal clinically important difference; PBO, placebo; QVA149, indacaterol/glycopyrronium; SAL, salmeterol; SGRQ, St George’s Respiratory Questionnaire; TDI, transitional dyspnea index; TIO, tiotropium; UMEC, umeclidinium; VI, vilanterol.