Table 2.
Effective Sample Size for Association Test
|
Method |
Percent of Samples Contaminated |
||||||
|---|---|---|---|---|---|---|---|
| 5% | 10% | 25% | 50% | 75% | 90% | 100% | |
| Low-Pass | |||||||
| Adjusted | 194 | 194 | 193 | 192 | 191 | 190 | 190 |
| Ignored | 193 | 193 | 190 | 186 | 182 | 179 | 177 |
| Dropped | 184 | 174 | 144 | 96 | 47 | 18 | 0 |
| High-Depth | |||||||
| Adjusted | 195 | 195 | 195 | 194 | 194 | 193 | 193 |
| Ignored | 195 | 194 | 192 | 189 | 186 | 184 | 182 |
| Dropped | 186 | 176 | 146 | 98 | 48 | 18 | 0 |
Shown here are the effective sample size estimates when α = 10% and total sample size is 198 under three scenarios: all samples included and adjusted with our method (“adjusted”), all samples included but contamination ignored (“ignored”), and contaminated samples removed from analysis (“dropped”).