Skip to main content
. 2015 Aug 6;97(2):284–290. doi: 10.1016/j.ajhg.2015.07.002

Table 2.

Effective Sample Size for Association Test


Method
Percent of Samples Contaminated
5% 10% 25% 50% 75% 90% 100%
Low-Pass

Adjusted 194 194 193 192 191 190 190
Ignored 193 193 190 186 182 179 177
Dropped 184 174 144 96 47 18 0

High-Depth

Adjusted 195 195 195 194 194 193 193
Ignored 195 194 192 189 186 184 182
Dropped 186 176 146 98 48 18 0

Shown here are the effective sample size estimates when α = 10% and total sample size is 198 under three scenarios: all samples included and adjusted with our method (“adjusted”), all samples included but contamination ignored (“ignored”), and contaminated samples (αˆ>0.01) removed from analysis (“dropped”).