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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Mol Cancer Res. 2015 Jun 3;13(9):1274–1282. doi: 10.1158/1541-7786.MCR-15-0061

Figure 1. Expression of FLT1P1 in human CRC cell lines.

Figure 1

A In the human genome, FLT1/VEGFR1 is located at chromosome 13q12, whereas FLT1P1 resides at chromosome 3p21.3. FLT1P1 is an intron-free processed pseudogene. It is homologous to the VEGFR1 cDNA from exon 20 to 30.

B Phylogenetic analysis of FLT1P1 showing that human FLT1P1 is closely related to chimpanzee orthologs.

C Three CRC cell lines (HCP1, SW480, and DLD1) expressed FLT1P1 ncRNA at variable basal levels according to a custom TaqMan qPCR assay.

D HCP1, SW480, and DLD1 cells had medial to high levels of VEGFR1 mRNA expression according to a TaqMan qPCR assay.