Figure 2.

Trans-ethnic PAINTOR Is Most Efficient in Identifying Causal Variants

The distributions of the number of SNPs required for follow-up identification of 90% of the causal variants across 1,000 simulations are displayed as boxplots. The different panels represent increasing levels of effect-size heterogeneity by ancestry: none (left), weak (middle), and strong (right). The widths of the notches in each boxplot roughly correspond to 95% confidence intervals for the median number of SNPs required for resolving 90% of the causal variants. For the sake of clarity, we have cut the y axis to emphasize the significant difference in performance across all three methods.