Table 2. Association of genotypes with BMI SDS and lipid phenotypes.
Phenotype | Variant | N | Beta | SE | CI | p-value |
---|---|---|---|---|---|---|
BMI SDS | rs599839 | 576 | -0.087 | 0.066 | [-0.217;0.044] | 0.193 |
BMI SDS | rs3846663 | 572 | 0.076 | 0.061 | [-0.045;0.196] | 0.219 |
BMI SDS | rs3812316 | 564 | -0.126 | 0.095 | [-0.312;0.06] | 0.184 |
BMI SDS | rs174570 | 578 | 0.176 | 0.09 | [-0.001;0.353] | 0.052 |
BMI SDS | rs4420638 | 584 | -0.004 | 0.079 | [-0.16;0.152] | 0.958 |
BMI SDS | rs6102059 | 575 | 0.062 | 0.065 | [-0.065;0.19] | 0.335 |
TC | rs599839 | 576 | -0.257 | 0.067 | [-0.389;-0.125] | 1.50x10 -4 |
TC | rs3846663 | 572 | 0.141 | 0.062 | [0.019;0.263] | 0.024 |
TC | rs3812316 | 564 | -0.022 | 0.094 | [-0.207;0.162] | 0.812 |
TC | rs174570 | 578 | -0.04 | 0.092 | [-0.22;0.14] | 0.662 |
TC | rs4420638 | 584 | 0.336 | 0.079 | [0.181;0.491] | 2.45x10 -5 |
TC | rs6102059 | 575 | 0.019 | 0.065 | [-0.109;0.146] | 0.775 |
HDL-C | rs599839 | 576 | 0.077 | 0.067 | [-0.054;0.207] | 0.25 |
HDL-C | rs3846663 | 572 | 0.098 | 0.061 | [-0.021;0.217] | 0.106 |
HDL-C | rs3812316 | 564 | 0.129 | 0.093 | [-0.054;0.312] | 0.168 |
HDL-C | rs174570 | 578 | -0.078 | 0.09 | [-0.254;0.098] | 0.387 |
HDL-C | rs4420638 | 584 | -0.13 | 0.078 | [-0.283;0.024] | 0.098 |
HDL-C | rs6102059 | 575 | 0.038 | 0.064 | [-0.087;0.164] | 0.547 |
LDL-C | rs599839 | 576 | -0.3 | 0.067 | [-0.431;-0.168] | 8.82x10 -6 |
LDL-C | rs3846663 | 572 | 0.12 | 0.062 | [-0.002;0.241] | 0.054 |
LDL-C | rs3812316 | 564 | -0.043 | 0.094 | [-0.226;0.141] | 0.649 |
LDL-C | rs174570 | 578 | 0.021 | 0.091 | [-0.158;0.2] | 0.817 |
LDL-C | rs4420638 | 584 | 0.382 | 0.078 | [0.228;0.536] | 1.38x10 -6 |
LDL-C | rs6102059 | 575 | 0.018 | 0.065 | [-0.109;0.145] | 0.781 |
TG | rs599839 | 576 | -0.114 | 0.065 | [-0.241;0.014] | 0.081 |
TG | rs3846663 | 572 | -0.006 | 0.059 | [-0.123;0.11] | 0.913 |
TG | rs3812316 | 564 | -0.134 | 0.088 | [-0.307;0.038] | 0.127 |
TG | rs174570 | 578 | 0.137 | 0.087 | [-0.034;0.307] | 0.116 |
TG | rs4420638 | 584 | 0.135 | 0.076 | [-0.014;0.285] | 0.076 |
TG | rs6102059 | 575 | 0.075 | 0.062 | [-0.046;0.197] | 0.225 |
We present numbers of cases available for the corresponding analysis (N), beta-coefficients, their standard errors (SE), 95% confidence intervals (CI) and uncorrected p-values. Since standardized values were analysed, beta-coefficients and standard errors have unit 1. BMI SDS was analysed with the additive model adjusted for age and sex. Lipid phenotypes were logarithmized and analysed with the additive model adjusted for age, sex and BMI SDS. Associations significant after correction for multiple testing (see methods section) are printed in bold.