Skip to main content
. Author manuscript; available in PMC: 2015 Sep 17.
Published in final edited form as: Biochemistry. 2015 Sep 2;54(36):5617–5631. doi: 10.1021/acs.biochem.5b00407

Figure 2.

Figure 2

Expression of XLPP variants in mammalian cells results in accumulation of PPIX. HeLa cells are indicated by vertical-striped bars, while K562 cells are represented by checkered bars. The graph bars correspond to the results with wild-type hALAS2 (blue), delAT (green), delAGTG (pink), and Q548X (purple). Mean PPIX fluorescence values are representative of three separate experiments ± standard deviation (*p<0.05 and **p<0.01, Student’s t-test) [a.u., arbitrary units].