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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Horm Behav. 2015 Jul 14;74:173–185. doi: 10.1016/j.yhbeh.2015.06.022

Figure 1. Choice Reaction Task.

Figure 1

Median motor reaction time difference scores (in milliseconds) following 3 months of 1 mg oral estradiol or placebo treatment and after exposure to anti-cholinergic challenge. Paired bars represent reaction time difference from placebo challenge following each drug challenge by long-term treatment (estradiol or placebo). Positive difference score indicates a slowing of RT (impaired performance) after drug compared to placebo challenge. SCOP = scopolamine; MECA = mecamylamine. Doses are μg/kg for intravenous scopolamine and oral milligram dosage for mecamylamine. F(1,12) = 7.71, p < .05 for main effect of estradiol treatment. Reproduced with permission from (Dumas et al., 2006).