Figure 3. Selective Reminding Task.
Recall failure difference scores following 3 months of 1 mg oral estradiol or placebo treatment and after exposure to anti-cholinergic challenge. Paired bars represent total recall failure difference from placebo challenge following each drug challenge by long-term treatment (estradiol or placebo). Greater impairment indicated by greater positive difference score. SCOP = scopolamine; MECA = mecamylamine. Doses are μg/kg for intravenous scopolamine and oral milligram dosage for mecamylamine. F(1,14) = 4.82, p < .05 for treatment by mecamylamine challenge dosage interaction. Reproduced with permission from (Dumas et al., 2006).