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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Horm Behav. 2015 Jul 14;74:173–185. doi: 10.1016/j.yhbeh.2015.06.022

Figure 6. Virtual Morris Water Maze.

Figure 6

(modified from Newhouse et al., 2013):

A. Platform latency during learning trials after mecamylamine 10 mg challenge. Filled triangle represents long-term placebo treatment. Filled squares represent long-term tamoxifen 10 mg treatment. F(1,14) = 6.6, p=.024 for main effect of tamoxifen treatment. B. Time spent in correct quadrant during the probe trial; difference from placebo challenge during mecamylamine challenge (10 mg). Crosshatch bar represents placebo long-term treatment and dark bar represents tamoxifen 10 mg oral long-term treatment. F(1,67) = 6.28, p<.01 for main effect of tamoxifen treatment.