Table 2.

T2 relaxation time and WORMS grades by quartile of average daily minutes of moderate to vigorous physical activity

	Average daily minutes of moderate to vigourous activity
	1. quartile (lowest)	2. quartile	3. quartile	4. quartile (highest)	p
	n = 68	n = 69	n = 69	n = 68
Meniscus
WORMS max	1.43 (0.24)	1.60 (0.22)	1.78 (0.23)	1.98 (0.22)	0.0087
WORMS sum	2.04 (0.53)	2.70 (0.49)	2.85 (0.51)	3.31 (0.49)	0.0089
Sum. of lesions Medial Meniscus	1.19 (0.43)	1.52 (0.41)	1.76 (0.42)	2.42 (0.40)	0.0017
Sum. of lesions Lateral Meniscus	0.84 (0.29)	1.16 (0.28)	1.09 (0.28)	0.89 (0.27)	0.9266
Cartilage
WORMS max	3.10 (0.39)	2.94 (0.32)	3.08 (0.32)	3.43 (0.31)	0.2477
WORMS sum	5.9 (0.73)	5.7 (0.68)	5.5 (0.71)	6.4 (0.67)	0.5813
BMEP
WORMS max	1.1 (0.20)	1.0 (0.19)	1.3 (0.19)	1.5 (0.19)	0.0053
WORMS sum	1.6 (0.34)	1.4 (0.32)	2.1 (0.33)	2.1 (0.31)	0.0498
T2 (ms)
LFC	35.8 (0.44)	36.6 (0.42)	36.4 (0.42)	36.5 (0.39)	0.1292
LT	29.5 (0.48)	30.3 (0.44)	30.2 (0.46)	30.3 (0.43)	0.131
MFC	38.1 (0.54)	38.5 (0.51)	38.9 (0.51)	38.8 (0.48)	0.102
MT	30.7 (0.43)	31.7 (0.41)	31.4 (0.42)	31.8 (0.39)	0.027
P	34.4 (0.6)	35.0 (0.61)	34.3 (0.62)	35.1 (0.59)	0.495
Average of all regions	33.8 (0.38)	34.7 (0.35)	34.4 (0.35)	34.6 (0.32)	0.054

Least square means (Std error), adjusted for age, sex, BMI, family history of knee replacement, history of knee surgery or injury, WOMAC pain, stiffness and disability (bilateral) hip and ankle pain (bilateral), average daily wear time of accelerometer. WORMS max = highest score in any subcompartment. WORMS sum score = sum of individual subcompartments. Bold numbers are statistically significant (p < 0.01), italic numbers are trends (p < 0.05). BMEP = bone marrow edema pattern. LFC = lateral femoral condyle, LT = lateral tibia, MFC = medial femoral condyle, MT = medial tibia, P = patella